19 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Three syndromes ... child * Severe cases ... AFLP #Obstetrics #OBGyn ... #Hematology #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP Syndrome ... (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP Syndrome ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Differential Diagnosis Algorithm ... TTP) • HELLP syndrome ... #Causes #Obstetrics ... #OBGyn
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... antiphospholipid syndrome ... - Pregnancy: HELLP ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Causes of Growth Discrepancy: Large for Gestational Age - Differential Diagnosis Algorithm
Maternal Factors:
 • Multiparity
 •
Causes of Growth ... Differential Diagnosis Algorithm ... over course of pregnancy ... #Causes #Obstetrics ... #OBGyn
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Rare • Drugs (e.g ... #Causes #Hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Differential Diagnosis Algorithm ... Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... #Causes #Hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... Hemolytic uremic syndrome ... differential #diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... • Secondary (e.g ... Hypothyroid • Pregnancy ... #Causes #Hematology