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diagnosis algorithm lupus sle anemia causes criteria classification oncology vasculitis autoantibodies calculation deficiency dermatology dermatosis diffuse enlarged eularacr febrile ferritin
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Normal RBCs • Acute ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Inflammatory • Systemic ... Lupus Erythematosus ... Serum Sickness Hemolytic ... Algorithm #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Deficiency Anemia - Differential ... • Blood loss: GI ... bleed, GU bleed ... extravascular) hemolysis ... Algorithm #ferritin #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Lupus Erythematosus ... discoid lupus, Acute ... Thrombocytopenia, Autoimmune hemolysis ... #diagnosis #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Reactive: - Systemic ... Inflammatory • Systemic ... Lupus Erythematosus ... Fatigue • Acute ... Algorithm #Causes #Hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... Lupus Erythematosus ... CLINICAL CRITERIA - ACUTE ... NEUROLOGIC - HEMOLYTIC ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Lymphadenopathies 7% - Hemolytic ... (aPL) 30-45% Differential ... #Lupus #Erythematosus ... #rheumatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Index > 3: • Acute ... loss: Trauma, Gl bleed ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Pleural effusions • Acute ... pericardial/abd GI ... #Diagnosis #Rheumatology
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