22 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Normal CK - Myositis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... , Arthralgia / arthritis ... , Myositis Dr ... #Symptoms #diagnosis ... #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
of giant cell arteritis ... ESR and/or CRP Temporal ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
associated with temporal ... arteritis Inclusion ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of hip (rare), Arthritis ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... ) Arteritis: Pathogenesis ... yrs old; F>M Signs ... #Arteritis #Pathophysiology ... #Diagnosis #Signs
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... , and arthritis ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
: - Arthritis ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... RA) or systemic lupus ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms