25 results
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
Antimalarial drugs ... QRS #widening #ECG ... #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential
Torsades de Pointes 
•Precipitated by drugs that prolong the QT interval 
•Class IA antidysrhythmics (procainamide, quinidine)
Precipitated by drugs ... hypomagnesemia, hypokalemia ... TorsadesDePointes #Diagnosis ... #Cardiology #ECG ... #EKG
Osborn (J Wave)

Etiology 
• Hypothermia (below 320C / SOOF) 
• Normal variant 
• Hypercalcemia 
• Neurological
Normal variant • Hypercalcemia ... Neurological insult • Medications ... Osborn #JWave #Diagnosis ... #Differential #Cardiology ... #EKG #ECG #Hypothermia
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Antihypertensive Drugs ... failure - Co-medication ... (e.g. statins, ... antihypertensive #medications ... contraindications #table
Torsades de Pointes
• "Twisting of the pointes" 
• QRS axis swings from positive to negative direction
precipitated by drugs ... Hypomagnesemia Hypokalemia ... TorsadesDePointes #Diagnosis ... #Cardiology #ECG ... #EKG
Osborn waves - positive deflections at the J point (negative in aVR and V1) with a
brain injury, medications ... This EKG was recorded ... #EKG #EmergencyMedicine ... #Cardiology #diagnosis ... Electrocardiogram #ECG
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Infiltrative disorders (e.g ... in kidneys) - Medications ... (e.g. lithium, ... renal diseases (e.g ... #Table #Causes
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
calcineurin inhibitors (e.g ... Sympathomimetics (e.g ... anticholinergic effects (e.g ... #Drugs #pharmacology ... #differential #diagnosis
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
are usually the drugs ... with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... #table #pharmacotherapy
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications