6742 results
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
- Differential Diagnosis ... Hypovolemia • RAAS inhibitor ... • Calcineurin inhibitor ... blockers - MCW Nephrology ... #Differential #Diagnosis
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Hyperparathyroidism, TKI, ALK inhibitor ... #Differential #Diagnosis ... #Algorithm #nephrology
Causes of Non-Gap Metabolic Acidosis - Differential Diagnosis Algorithm
Normal Anion Gap (<14) (Loss of Bicarbonate) -
- Differential Diagnosis ... Carbonic anhydrase inhibitor ... MetabolicAcidosis #NonGap #Nephrology ... #Differential #Diagnosis
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Extrarenal Proton pump inhibitor ... #differential #diagnosis ... #nephrology #Causes
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... of aldosterone inhibition ... #differential #diagnosis
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
actually a protease inhibitor ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... because of the CYP inhibition
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 inhibitor ... Dipyridamole - PDE5 inhibition ... (and PDE3 inhibition ... Cilostazol - PDE3 inhibition
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
Prostaglandin inhibition ... HTN, Edema • Inhibition ... KidneyDisease #nephrology
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
Inhibition of this ... druginformation #nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
carbonic anhydrase inhibitor ... #pharmacology #nephrology