38 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... PT, aPTT(liver disease ... test, ANA (e.g., SLE ... bypass), LFT (liver disease ... #Workup #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Metastatic Disease ... #Workup #Differential ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Metastatic Disease ... #Workup #Differential ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
• Gaucher's Disease ... Glycogen Storage Disease ... Sickness Hemolytic Disease ... • Sickle Cell Disease ... #Causes #Hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... intake) • Target blood ... Insufficient blood ... #rheumatology # ... pharmacology #levels #lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Anemia of Chronic Disease ... Anemia of Chronic Disease ... Renal Disease, Liver ... Disease, Endocrinopathy ... #Causes #Hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... Vasculitides, IBD, Celiac disease ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology