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diagnosis differential hematology treatment clinical algorithm criticalcare radiology workup nephrology orthopedics neurology checklist lupus video pharmacology anesthesia anesthesiology dermatology physicalexam
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... ANA (anti-nuclear ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... and probably < ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Differential Diagnosis: Rheumatologic ... - MCC systemic ... sclerosis, RA, SLE ... , Sjogren syndrome ... Antisynthetase syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Management Summary ... Workup: - ANA ... Positive in 60-80% of cases ... Usual therapeutic management ... #Summary #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... ), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... scleroderma) - Anti-Scl ... • Sjögren syndrome ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... ARUPConsult @ARUPLabs #ANA ... differential #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
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