28 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... /dL or CC < 40 ml ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... (HCV) • CLL & MBL ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Systemic Lupus ... Lymphocytes) - Monoclonal ... Algorithm #Causes #Hematology ... #Oncology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... change disease • Hematologic ... Capillary leak syndrome ... • Tumor lysis syndrome ... #AKI #Cancer #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #Systemic #Lupus ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management