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diagnosis management differential oncology algorithm causes sle erythematosus cll leukemia lymphocytic mds myelodysplastic syndrome systemic thrombocytosis workup activation approach arthritis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... Medicine @SCVMCMed #Aplastic ... #management #treatment ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Deficiency • Aplastic ... Anemia • Anemia ... of Chronic Disease ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Polycythemia Vera • Chronic ... : • Acute or Chronic ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... • Marrow Aplasia ... RA, SLE, PRV, Chronic ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
of chronic inflammation ... deficiency (including chronic ... deficiencies: Chronic ... marrow failure: Aplastic ... Production #Index #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... mutations) • Immune Aplastic ... anemia Treatment ... #hematology #diagnosis
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... - CHRONIC CUTANEOUS ... NEUROLOGIC - HEMOLYTIC ANEMIA ... absence of hemolytic anemia ... #Diagnosis #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... BaillouChloe #Lupus ... Nephritis #Management #treatment ... #management #rheumatology
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