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differential rheumatology treatment causes algorithm syndrome arthritis disease leukemia symptoms aplastic classification cll lymphocytic rheumatoid workup 1 abscess aih apml
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... Iron deficiency anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Fatigue • Acute ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Chronic ... Index > 3: • Acute ... Production #Index #hematology ... #diagnosis #calculation
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... progress to MDS or acute ... #diagnosis #management ... #treatment #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... anorexia, ARDS ​• RBC ... severe hemolytic anemia ... Nodular → Mular DIAGNOSIS ... #management #Bartonella
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... #management #hematology ... #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... Blood #Disorders #hematology
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