38 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
TTP, HUS, DIC, HELLP ... , Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... Elevated Liver tests ... AFLP #obstetrics #hematology ... #diagnosis #table
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #hematology #hemolysis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... LAC) • Sjogren Syndrome ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP ... Syndrome • TTP ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... syndrome - ... Hemolytic uremic syndrome ... #hematology #anemia