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differential causes algorithm hepatology hepatorenal hrs kidney renal syndrome akd biomarkers chronic definitions framework hrsaki hrsckd hrsnaki hyperkalemia hyperphosphatemia k
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
): • GFR < 60 ... • GFR < 60 ml/min ... • Decrease in GFR ... ): • GFR ≥ 60 ... #nephrology #acute
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... Kidney #renal #diagnosis ... #laboratory #nephrology
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
maintaining baseline GFR ... setting of modest GFR ... GFR > 30 and complete ... avoidance with GFR ... Kidney #renal #nephrology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
(Acute: previously ... e.g. diuretics, NSAIDs ... Type 2) • HRS-AKD ... months - eGFR ... - eGFR < 60ml
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... NSAlDs, antibiotics ... Abhilash Koratala @NephroP ... #Acute #KidneyInjury ... #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... Nephritis • Drugs (NSAlDs ... #Acute #KidneyInjury ... #Nephrology #Differential ... #Diagnosis #Algorithm
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Kidney Disease: • AKI ... , CKD Increased ... Hypoparathyroidism, Acromegaly, FGFR ... Workup #phosphate #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... kidney function (eGFR ... eosinophiluria) • Drugs (NSAlDs ... Hyperphosphatemia #CKD ... KidneyDisease #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
hepatitis, or acute ... dominates → ↓ GFR ... Diagnosis (Clinical ... Syndrome #Hepatology #Nephrology ... #Diagnosis
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