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nephrology diagnosis differential algorithm pharmacology workup akd biomarkers chronic comparison complications definitions effects framework gout hepatology hepatorenal hrs hrsaki hrsckd
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
, CKD, AKD Acute ... • GFR < 60 ml/min ... • GFR < 60 ml/min ... • Decrease in GFR ... • GFR ≥ 60 ml/min
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Diagnostic Criteria HRS-AKI ... Type 2) • HRS-AKD ... months - eGFR ... ascites • HRS-CKD ... - eGFR < 60ml
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
perfusion of remaining nephrons ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Kidney Injury (AKI ... Kidney Injury ( ... AKI) - Acute increase ... #Acute #KidneyInjury
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... Acute Kidney Injury ... Abhilash Koratala @NephroP ... #AKI #causes ... #Acute #KidneyInjury
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Kidney Disease ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Disease: • AKI ... , CKD Increased ... Renal Phosphate ... Hypoparathyroidism, Acromegaly, FGFR
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... myoglobin • Myeloma ... cardiac imaging #Acute ... #Kidney #Injury
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... Release of purine bases
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