19 results
diagnosis causes hypercalcemia algorithm calcium management pth hypocalcemia acquired acromegaly anemia bone bonestrength disorders encephalopathy feedbackloop femur fractures gh growthhormone
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Miscellaneous - Bone ... Hypercalcemia #Differential ... Algorithm #causes #endocrinology
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Hypercalcemia #Malignancy #Pathophysiology ... #Differential #
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
- Accelerated Bone ... Formation: Hungy Bone ... Diagnosis #Management #endocrinology ... #differential #
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
- Hormones and Pathophysiology ... Calcitriol: • Bones ... : ↑ Bone resorption ... Hypercalcemia #Hormones #Pathophysiology ... #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Hypercalcemia - Differential ... Cytokine-Mediated Bone ... Lymphomas) Metastatic Bone ... Hypercalcemia #Differential ... Diagnosis #Algorithm #Endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... #FeedbackLoop #endocrinology ... #pathophysiology
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
D) Increased bone ... Paget's disease of bone ... Multiple myeloma (bone ... Hypercalcemia #Causes #endocrinology ... #diagnosis #differential
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
due to increased bone ... Hypercalcemia #Causes #differential ... calcium #high #endocrinology
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