62 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased WBCs ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... Algorithm #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Dehydration • Symptoms ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... T-cell - CD7, CD3 Chronic ... (+) ↑ WBC ... Blood #Disorders #hematology ... #Differential #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... if high risk if WBC ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... #management #hematology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout Diagnosis ... treatment • Chronic ... Urate nephropathy, renal ... #management #treatment ... #ULT #rheumatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Burr cells - Renal ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Relative - Normal RBC ... Chest Symptoms ... Sleep Apnea • Chronic ... Algorithm #Causes #Hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... or 0.5 g/day → renal ... #treatment #management ... #rheumatology # ... nephrology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... TerrierBen #Renal ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology # ... Cryoglobulinemic #Nephrology