32 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... Diagnosis and Lupus ... #differential #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... , others (RNP, aPL ... glycoprotein I (ß2GP), Lupus ... Autoantibodies #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Disease, PRES Pathophysiology ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... especially in the wrists ... pericarditis » is...lupus ... search ANA and aPL ... erythematosus #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... Usual therapeutic management ... #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... diagnosis #algorithm #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... BaillouChloe #Lupus ... #Nephritis #Management ... #rheumatology #
Fatigue in Systemic lupus

Dr. Laurent ARNAUD @Lupusreference

#Fatigue #lupus #pathophysiology #rheumatology
Fatigue in Systemic lupus ... Lupusreference #Fatigue #lupus ... #pathophysiology ... #rheumatology