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diagnosis differential management rheumatology algorithm causes pharmacology treatment table clinical sle medications erythematosus nephrology pathophysiology hematology dermatology neurology systemic classification
Sleep Regulation of sleep is critical for life! Ever wonder why you can’t fall asleep while hungry
hungry or why anti-histamines ... #Sleep #anti-histamine
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 5-10% - Anti- ... Diagnosis and Lupus ... : Drug-induced lupus ... SLE #Systemic #Lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... & drug-induced lupus ... SCLE, neonatal lupus ... Sjogren and neonatal lupus
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... , Anti-Ro (SSA) ... and Anti-La (SSB ... glycoprotein I (ß2GP), Lupus ... (SSA), Anti-La
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... sle #systemic #lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Epidemiology: -10% of all lupus ... years) Systemic Lupus ... , oral ulcers, Lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... IgG > 40 GPL or anti-ß2GPI ... antibodies domain: Anti-dsDNA ... antibody, Anti-Sm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... Lupusreference #SLE #lupus
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Elevated CK, +Anti-Jo ... Elevated CK, +Anti-Jo ... , +Anti-Mi2 Polymyalgia ... , Gemcitabine Lupus ... uncommon 5-15% of lupus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... reference range - Anti-dsDNA ... tested by ELISA) - Anti-Sm
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