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diagnosis rheumatology erythematosus systemic differential comparison antibodies autoantibodies classification management pharmacology ana antinuclear associations diseases druginduced criteria medications nephrology summary
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... , neonatal lupus ... 5-15% If SLE is ... #rheumatology #table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... are evocative of SLE ... management of SLE ... #sle #comparison ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... (SLE): ANA (anti-nuclear ... , Anti-Ro (SSA) ... glycoprotein I (ß2GP), Lupus ... #associations #table
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... Diagnosis and Lupus ... Lupusreference #SLE ... #Systemic #Lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... , oral ulcers, Lupus ... are evocative of SLE ... #lupus #Systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... screening test Anti-dsDNA ... • Specific for SLE ... #Systemic #Lupus ... Erythematosus #SLE
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... #IMDAMNSHARP #sle ... #systemic #lupus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic Lupus ... reference range - Anti-dsDNA ... tested by ELISA) - Anti-Sm ... #Rheumatology #SLE
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... - SLE Anti-histone ... - Drug-induced SLE ... - SLE Anti-SSA ... diseases #diagnosis #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... IgG > 40 GPL or anti-ß2GPI ... antibodies domain: Anti-dsDNA ... antibody, Anti-Sm ... Classification #Criteria #SLE
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