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Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... aneurysm: Causes arterial ... - TMA: TTP - Arterial ... , HUS, DIC #Arterial ... #clots #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Myeloproliferative disease ... • Nephrotic Syndrome ... Fat Emboli ARTERIAL ... THROMBOSIS Arterial ... pathophysiology #hematology
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
Hepatopulmonary Syndrome ... Diseases of the ... Patients with liver disease ... Alveolar-arterial ... #HPS #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL-1B, ATRA ... #Algorithm #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Scl-70 - Scleroderma ... - Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... venous thromboses, arterial ... #disease #Diagnosis ... #criteria #rheumatology
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... of the digital arteries ... and arterioles (e.g ... #disease #phenomenon ... fingers #hands #rheumatology
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... of the digital arteries ... and arterioles (e.g ... #disease #phenomenon ... fingers #hands #rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Infectious • Bacterial ... • Thrombus (e.g ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Hypercoagulable State Arterial ... risk actor for arterial ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE