117 results
diagnosis differential causes signs symptoms hematology management msk orthopedics endocrinology workup complications anemia nephrology syndrome hepatology oncology pharmacology calcium fractures
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Hypercalcemia - ... Differential Diagnosis Algorithm ... Cytokine-Mediated Bone ... Lymphomas) Metastatic Bone ... Differential #Diagnosis #Algorithm
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of ... Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Differential #Diagnosis #algorithm
Hypercalcemia - Hormones and Pathophysiology Calcitriol: • Bones: Enhances mineralization • GI Tract: ↑ Ca2+
Calcitriol: • Bones ... PO4- PTH: • Bones ... : ↑ Bone resorption ... Calcitonin: • Bones ... : ↓ Bone resorption
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... Differential Diagnosis Algorithm ... Miscellaneous - Bone ... Hyperthyroid, Bony ... Differential #Diagnosis #Algorithm
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
Calcium - Net Effect Hypercalcemia ... absorption ↑ bone ... Hypophosphatemia: ↑ bone ... Calcium #Phosphorus #pathophysiology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
28% (bone demineralization ... • Anemia 78% (bone ... macrocytic • Bone ... Diagnosis - Clonal bone ... clonal cell in bone
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... Peri-articular osteopenia (bones ... Radiology #Clinical #Pathophysiology
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... due to increased bone ... Immobilization Hypercalcemia ... : • Familial hypercalcemic
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Hypocalcemia - Diagnosis ... - Accelerated Bone ... Formation: Hungy Bone ... PTH Signaling #Hypocalcemia ... #differential #algorithm
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
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