11 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
mortality, and ... Microangiopathy #thrombocytopenic ... HemolyticUremicSyndrome #HUS #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... and Pregnancy - ... Bloodman #Pregnancy #Thrombocytopenia ... AFLP #obstetrics #hematology ... #diagnosis #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... Negative association ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
triad of MAHA + thrombocytopenia ... metabolism and ... There is a high association ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
clinical associations ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Anti-MDA5, anti-Mi ... Pattern: Proximal and ... #differential #diagnosis ... #comparison #rheumatology ... #table