49 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
failure, Addison's disease ... )-alkali syndrome ... #differential #diagnosis ... #calcium #high ... #endocrinology
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory ... Hypoparathyroidism - Calcium-sensing ... Chronic kidney disease ... Hyperparathyroidism #Diagnosis ... #Endocrinology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... Activation: Liver disease ... , Kidney Disease ... - Calcium Sequestration ... #endocrinology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... Calcium-containing ... the first-line treatments ... #Pharmacology #Pathophysiology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Diagnosis Algorithm ... Phenytoin, Nephrotic Syndrome ... Hepatobiliary Disease ... Algorithm #Phosphate #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Granulomatous Disease ... Bony Mets - Calcium ... #Differential #Diagnosis ... Algorithm #causes #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... #Hypercalcemia ... #Differential #Diagnosis ... #Endocrinology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... 4.6 mg/dL • Calcium ... • Hypocalcemia ... - Calcium gluconate ... #TLS #diagnosis
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis ... Autosomal Dominant Calcium ... Other • Excess Calcium ... #Differential #Diagnosis ... #Algorithm #Endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Lithium use • Calcium-sensing ... Chronic kidney disease ... • Milk-alkali syndrome ... #Causes #endocrinology ... #diagnosis #differential