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differential hematology ana antinuclear erythematosus lupus testing management patterns systemic vasculitis workup antibodies autoantibodies classification criteria 4tscore algorithm anca associations
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Wegener's granulomatosis ... polyangiitis U1-RNP antibody ... disease Endomyseal antibody ... Associations #diseases #diagnosis ... #table #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear Antibody ... in drug-induced SLE ... anti-topoisomerase antibody ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... (<1000/MM3) - THROMBOCYTOPENIA ... hemolytic anemia #Diagnosis ... #Rheumatology # ... SLE #Lupus #Erythematosus
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... DIC, TTP, HUS - Antibody-mediated ... - Autoimmune: SLE ... #Framework #hematology
Bayesian combination of 4T score with Heparin PF4 antibody titer to obtain the post-test probability of
with Heparin PF4 antibody ... PF4Antibody #Bayesian #Diagnosis ... #Hematology #HITT ... #Thrombocytopenia
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
Includes granulomatosis ... associated with PR3+ antibody ... associated with MPO+ antibody ... PANCA #MPO #PR3 #Diagnosis ... #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
domain: Leukopenia, Thrombocytopenia ... , Anti-Sm antibody ... Classification #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
4T Score for Heparin-Induced Thrombocytopenia Interpretation of the 4T score: 0-3 points: Low probability (<<1%) -
Heparin-Induced Thrombocytopenia ... check anti-PF4 antibody ... check anti-PF4 antibody ... #Diagnosis #Criteria ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Autoimmune • ITP • SLE ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... (anti-nuclear antibody ... Antiphospholipid Antibody ... #diagnosis #associations
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