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diagnosis hematology causes potassium hyperkalemia workup hemolytic classification extravascular hypokalemia intravascular mcv medications pancytopenia rheumatology systemic abnormal agglutinin allergy antibiotics
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... atypical HUS) - Drug-induced ... anemia" • HELLP ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... anemia • ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome ... infection) - Drugs ... Extravascular #Causes #differential ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Infection) High ... Deficiency • Drugs ... #Causes #Hematology
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... in Hemolytic Anemia ... #medications #Hemolytic ... #Anemia #differential ... #pharmacology #table
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... , CKD • Hemolytic ... Orotic aciduria, Drugs ... Diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , PCH, Evans Syndrome ... Defects: Sickle cell anemia ... #Differential # ... Diagnosis #hematology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic algorithm ... • Tumor lysis/hemolysis ... Normal, Renin High ... #nephrology #potassium ... #differential
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... Leukemia (CML) - Hemolytic ... Anemia - Others ... • High purine
Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Hypercalcemia - Differential ... Diagnosis Algorithm ... Immobilization, Drugs ... disease, Viral Syndromes ... #Workup #nephrology
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