24 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... the critically ill ... coagulation defects. 1) ... HELLP (Hemolysis ... AFLP #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
the critically ill ... coagulation defects. 1) ... HELLP (Hemolysis ... Pregnancy #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... (anti-nuclear antibody ... Antiphospholipid Antibody ... Myositis: Anti-JO-1, ... RNA Polymerase Ill
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
DIC, TTP, HUS - Antibody-mediated ... - Pregnancy: HELLP ... Diagnosis #Framework #hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
probability (<<1% ... check anti-PF4 antibody ... check anti-PF4 antibody ... Diagnosis #Criteria #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
activity (e.g. antibody ... to be normal. 1: ... 1 Mix of Patient's ... Study #diagnosis #hematology ... pathophysiology #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
gangrenosum • IBD ... Antiphospholipid-antibody ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework 1) ... TTP, HUS, DIC, HELLP ... Differential #Diagnosis #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Microangiopathy - TMAs 1. ... drug-associated TMA (antibody ... Microangiopathy #TMAs #hematology