25 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of Pregnancy ... the critically ill ... pregnant woman ... coagulation defects. 1) ... AFLP #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia and Pregnancy ... the critically ill ... pregnant woman ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... (anti-nuclear antibody ... Antiphospholipid Antibody ... Myositis: Anti-JO-1, ... RNA Polymerase Ill
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
DIC, TTP, HUS - Antibody-mediated ... antiphospholipid syndrome - Pregnancy ... Diagnosis #Framework #hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
probability (<<1% ... check anti-PF4 antibody ... check anti-PF4 antibody ... Diagnosis #Criteria #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
activity (e.g. antibody ... to be normal. 1: ... 1 Mix of Patient's ... Study #diagnosis #hematology ... pathophysiology #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Microangiopathy - TMAs 1. ... drug-associated TMA (antibody ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
gangrenosum • IBD ... Antiphospholipid-antibody ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Tropical sprue, IBD ... intake: Anorexia, Pregnancy ... Algorithm #ferritin #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology