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rheumatology differential erythematosus hematology signs syndrome symptoms treatment vasculitis oncology classification clinical complications druginduced pathophysiology summary activation antinxp2 antinxp2dm autoantibodies
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... months to years) Systemic ... Usual therapeutic management ... #rheumatology #diagnosis ... #management
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Lupus Erythematosus ... #SLE #hematology ... #differential #diagnosis ... #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 1 • Clinical Manifestations ... Positive in 60-80% of cases ... #lupus #Systemic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... autoantibodies that will cause ... #management #treatment
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Manifestations ... Myopathy (Also caused ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... , Cutaneous mimickers ... Lupusreference #SLE ... #Systemic #Lupus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin manifestations ... #Lupus #Erythematosus ... diagnosis #rheumatology ... #management
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... Vasculitis #dermpath #dermatology ... signs #lesions #diagnosis ... #clinical #manifestations
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... response -> Subacute cutaneous ... hair follicles -> causes ... pathophysiology #diagnosis
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
many differential diagnoses ... children (pediatric SLE ... to unexplained manifestations ... #diagnosis #sle ... #clues #system
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