16 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... La) - Sjogren's syndrome ... Anti-GBM - Goodpasture's ... #diagnosis #table ... #rheumatology #
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
TIF1y, NXP2, Mi-2, ... Anti-Synthetase Syndrome ... : Jo-1, PL7, PL12 ... clinical #diagnosis #rheumatology ... #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
of cases) 2. ... cases • Sjögren syndrome ... 1. ... + 90% • Anti-GBM ... antibodies #diagnosis #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
associations - 1. ... Infections 2. ... of symptoms - 1- ... Urticaria #diagnosis #rheumatology ... #comparison #table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... coagulation defects. 1) ... plasma exchange 2) ... #diagnosis #table ... #comparison
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
HSV-1 Frequently ... Mononucleosis-like disease ... Epstein—Barr virus EBV ... Microbiology #Diagnosis #Comparison ... #Table
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Vasoactive Drugs 1) ... Failure, Valvular Disease ... muscle rupture, VSD ... Pulmonary embolism 2) ... #table
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED ... A2 Age >75 2 ... Thromboembolism 2 ... V Vascular disease ... CHADS2VASc #HASBLED #Comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... coagulation defects. 1) ... plasma exchange 2) ... #Diagnosis #Comparison ... #Table
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma vs ... Non-Hodgkin's Lymphoma - Comparison ... (HIV, EN, HTLV-1, ... #NonHodgkins #comparison ... #differential #hematology