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Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... organic acids and bases ... tubule (DCT) - Active ... #Pathophysiology ... #Tubules #Table
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... failure (acute and chronic ... ) Causes of Non-anion ... Chronic progressive ... ketosis with ketone excretion
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal Excretion ... Kidney stones caused ... the Nonspecific Cation ... Diuretics #Renal #Excretion ... #Medications #Table
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... antidiuretic hormone secretion ... : • Acute or chronic ... #Causes #nephrology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Altered Renal Function ... and increased excretion ... AngiotensinII #Pathophysiology ... #Action
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Nasogastric suction ... antidiuretic hormone secretion ... Hypomagnesemia #Causes
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
 • Attempt vagal maneuvers
 • Give adenosine 6 milligrams IV
Treatment of Stable ... B-blockers with caution ... Treat underlying cause ... Treat underlying cause ... management #cardiology #algorithm
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings
Ileus: Functional bowel "blockage", no peristalsis
Mechanical Obstruction:
Findings Ileus: Functional ... either acute or chronic ... percussion • Nausea ... obstruction #sbo #ileus #pathophysiology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... loss: Nasogastric suction ... antidiuretic hormone secretion ... Hypomagnesemia #Causes
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... cells - ↑ Renin secretion ... adrenergic #receptors #actions ... #pharmacology #pathophysiology ... #comparison #table