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Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... of Action Diuretics ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... , Mechanism of Action ... empagliflozin LOOP DIURETICS ... Tolvaptan #Diuretics ... Pharmacology #summary #table
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action ... of Diuretics Amiloride ... Acetazolamide #Diuretics ... #Mechanism #Action ... #pharmacology #pathophysiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... ; High-Ceiling Diuretics ... the Nonspecific Cation ... #Medications #Table
Pharmacologic Treatments of Chronic Hypertension in Pregnancy
Central alpha-agonists
 - Methyldopa
 - Clonidine
Combined alpha- and beta-blocker
 -
Nifedipine (long-acting ... Hydralazine - Diuretics ... Pharmacology #HTN #Table
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Heart failure, Diuretics ... synthesis, leaving actions ... #Pharmacology #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
acid and most diuretics ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
 • Attempt vagal maneuvers
 • Give adenosine 6 milligrams IV
Treatment of Stable ... B-blockers with caution ... B-blockers with caution ... underlying cause #Stable ... management #cardiology #algorithm
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Antihypertensive Drugs Diuretics ... and physically active ... contraindications #table
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... adrenergic #receptors #actions ... #pharmacology #pathophysiology ... #comparison #table