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Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Pseudohyperparathyroidism, Renal ... #differential #diagnosis ... #calcium #high ... #endocrinology
Diagnosis of Hypokalemia - Differential Algorithm 

Categorized by Causes: Redistribution, Extrarenal Losses, Renal Losses (High and
Diagnosis of Hypokalemia ... Categorized by Causes ... Extrarenal Losses, Renal ... Losses (High and ... Blood Pressure) #Diagnosis
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
The Diagnostic Approach ... inhibitors Other causes ... cell disease - Renal ... transplant - SLE High ... #differential #causes
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential Diagnosis ... TTKG should be high ... #Algorithm #causes ... #potassium #high ... #pathophysiology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... breast, lung, renal ... lung cancer • Renal ... #endocrinology ... #diagnosis #differential
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... of High-anion Gap ... oxoproline) • Renal ... Renal acidosis ... #differential #diagnosis
Imaging Modalities for Renal Calculus

AXR. KUB
 - Good far calcium-containing stones useful when limited radiation dose
non-invasive - High ... identify non-calculus causes ... abdominal pain: diagnoses ... for non-calculus causes ... urinary tract: diagnostic
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
TSH low; free T4 high ... ; in some cases, ... and T3 normal or high ... #differential #diagnosis ... #endocrinology
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
Types of Renal Calculi ... Hypercalcemia, Renal ... Mycoplasma infections, High ... #differential #diagnosis ... #causes #calculus
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... Loop Diuretics; High-Ceiling ... Kidney stones caused ... Inhibitors of Renal