The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... GiantCell #Temporal #Arteritis ... #Pathophysiology ... #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
Septic Arthritis ... Notes: - Septic Arthritis ... S.A. can also be caused ... SepticArthritis #pathophysiology ... #diagnosis
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
their turn • Causes ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #signs #psychiatry ... #criteria
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... : - Coronary Arteritis ... #Diagnosis #Pathophysiology
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Psoriatic Arthritis ... Arthritis of DIP ... Arthritis mutilans ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... #pathophysiology ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... erythematosus (SLE) Signs ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs