The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms msk complications vasculitis ankylosingspondylitis chondrocalcinosis endocrinology extraarticular geriatrics pagetsdisease pseudogout psoriaticarthritis psychiatry ra rheumatoidarthritis temporal adhesivecapsulitis agammaglobulinemia alzheimersdisease avascularnecrosis
Falls: Pathogenesis and Complications Poly-pharmacy Disorders affecting movement and balance - Sensory deficits - Neuromuscular degeneration/Cerebrovascular disease -
Cerebrovascular disease ... - Parkinson's Disease ... - Arthritis ... Geriatrics #Falls #pathophysiology ... complications #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... GiantCell #Temporal #Arteritis ... #Pathophysiology ... #Diagnosis #Signs
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... like rheumatoid arthritis ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... polyarticular arthritis ... #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Psoriatic Arthritis: Pathogenesis and Clinical findings In tendons and connective tissues: • Enthesitis - Pain/tenderness over
Psoriatic Arthritis ... Arthritis of DIP ... Arthritis mutilans ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... GravesDisease #pathophysiology ... endocrinology #symptoms #signs ... #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... #pathophysiology ... #signs #symptoms
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