The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs pathophysiology complications arteritis temporal erythematosus bonetumors bony cranialarteritis dermatomyositis dm gastrointestinal giantcellarteritis malignant manifestations msk mucocutaneous musculoskeletal pm polymyalgiarheumatica
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #SLE #Gastrointestinal ... pathophysiology #signs #symptoms ... #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Lupus #Erythematosus ... pathophysiology #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs/Symptoms ... Stroke or TIA-like symptoms ... Hemorrhages #GiantCell ... Complications #Signs #Symptoms ... #diagnosis #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous ... pathophysiology #diagnosis ... #signs #symptoms
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
Upper Urinary Tract ... - Indwelling urinary ... usual defense system ... bacteriuria or cystitis (see ... Pathophysiology #Signs #Symptoms
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
cancerous cells from systemic ... more common than primary ... differently from primary ... Signs/Symptoms: ... Malignant #Radiology #Diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Subacute development, primarily ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Vasculitis
Takayasu’s Arteritis: Pathogenesis and clinical findings - Fatigue, weight loss, low grade fever, arthralgias - Incr
Syndrome - >10mmHg systolic ... commonly carotid) - Systemic ... Takayasus #Arteritis #Vasculitis ... #Diagnosis #Signs ... #Symptoms
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