20 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... inflammation (SLE ... • Prosthetic valve ... annulus valve: ... Regurgitation #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Origin (FUO) - Differential ... Autoimmune: • SLE ... • Infectious endocarditis ... #FUO #Chronic #Differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Fever (50%), Depression ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... - Bacterial endocarditis ... conditions #joint #pain ... #differential #
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... leaflets/chordae) - SLE ... disease Infective endocarditis ... atrial myxoma)/ball valve ... #diagnosis #differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... Regurgitation - Differential ... Acute Prosthetic Valve ... , Rheumatic Fever ... Inflammatory: Lupus
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... ; sometimes « viral ... 9) Unexplained fever
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Bradycardia - Differential ... Endocarditis + ... • Post cardiac/Valve ... Autoimmune: • SLE ... #diagnosis #causes
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Autoimmune: SLE ... - Mechanical: valve ... replacement, endocarditis