23 results
diagnosis management differential causes coagulation table dic disseminated hypercoagulable intravascular liver oncology acutephasereactants aih anemia antiphospholipid apls aptt autoimmune biliary
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... Plasma → Recheck abnormal ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
GI. uterine) Laboratory ... • Normal platelet ... PT/INR • Normal ... prolonged if very low factor ... Disease #Diagnosis #Hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
of coagulation factors ... , Can be normal ... of thrombin and factor ... Scoring #diagnosis #hematology ... #laboratory
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
not a major risk actor ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Differential Diagnosis Algorithm ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... - APTT < 1.5 x normal ... treatment #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
patientsl • Risk factors ... blood donor • Pathophysiology ... patients • Risk factors ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... and AST can be normal ... production of clotting factors ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Tests (LFTs) - Normal ... associated clotting factors ... #Tests #LFTs #Laboratory ... Interpretation #diagnosis #hepatology
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