21 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Differential Diagnosis ... lymphoproliferative syndrome Clinical ... • Malar rash - spares ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... activity Anti-Ro ... Hydroxychloroquine *Short ... #Erythematosus ... #SLE #Summary #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Disease, PRES Pathophysiology ... permeability Diagnosis ... #Erythematosus
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
- Differential Diagnosis ... Arthritis • Systemic Lupus ... Erythematosus ... Inflammatory #JointPain #MSK ... #Algorithm #Orthopedics
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... 40% Target: SS-A/Ro ... -15% If SLE is clinically ... #erythematosus ... #diagnosis #rheumatology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Pathomechanics and Clinical ... LowAnkleSprain #Sports ... #MSK #orthopedics ... Grading #Grades #Diagnosis ... #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... RA) or systemic lupus ... erythematosus ( ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Pathogenesis and clinical ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... #Dislocation #Diagnosis ... signs #symptoms #msk ... #orthopedics #pathophysiology