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diagnosis clinical differential management algorithm pocus causes ultrasound treatment cardiology peds infectiousdiseases signs pathophysiology pediatrics symptoms rheumatology pulmonary dermatology microbiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... GCA is almost never ... /Symptoms: - Fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
pro-inflammatory cytokines ... hemophagocytosis and cytokine ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever
Pathogenesis of Rheumatic Fever Pathogenesis of rheumatic fever. 1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... infiltration leading to cytokine-mediated ... #Rheumatic #Fever
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... Endotoxins, Toxins, Cytokines ... BrighamChiefs #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
activation and cytokine ... following: • Fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology: • Cytokine ... Subacute-Acute: • Common: fever
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
, seasonal hay fever ... cells secrete cytokines
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
the release of cytokines ... hypothalamus → fever
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
night sweats, fever ... ), Recombinant cytokines
Causes of Fever: IMADE Mnemonic INFECTION • Infection 1.0 - Common & Localizing: Base Rate • Infection
Causes of Fever: ... carcinomas present with fever ... increased inflammtory cytockines ... with DVT/PE + fever ... pheochromocytoma #Fever
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